Table 3 Heterogeneity and pleiotropy
From: Impulsivity and epilepsy: a bidirectional mendelian randomization study
Heterogeneity | Pleiotropy | ||
|---|---|---|---|
MR Egger | IVW | MR-PRESSO | |
Exposure | |||
IAF | 0.443 | 0.477 | 0.669 |
ICF | 0.555 | 0.577 | 0.471 |
IPF | 0.108 | 0.116 | 0.459 |
IA-NGTA | 0.252 | 0.273 | 0.551 |
IA-GTA | 0.220 | 0.169 | 0.097 |
DRD | 0.603 | 0.576 | 0.221 |
DRD-SMR | 0.991 | 0.993 | 0.703 |
DRD-MMR | 0.392 | 0.432 | 0.742 |
DRD-LMR | 0.993 | 0.982 | 0.090 |
Negative urgency | 0.297 | 0.262 | 0.190 |
Lack of perseverance | 0.819 | 0.808 | 0.273 |
Lack of premeditation | 0.380 | 0.176 | 0.014 |
Positive urgency | 0.469 | 0.430 | 0.176 |
Sensation seeking | 0.616 | 0.647 | 0.572 |
Outcome | |||
IAF | 1.000 | 1.000 | 0.905 |
ICF | 1.000 | 1.000 | 0.948 |
IPF | 1.000 | 1.000 | 0.896 |
IA-NGTA | 1.000 | 1.000 | 0.964 |
IA-GTA | 1.000 | 1.000 | 0.902 |
DRD | 1.000 | 1.000 | 0.931 |
DRD-SMR | 1.000 | 1.000 | 0.841 |
DRD-MMR | 1.000 | 1.000 | 0.946 |
DRD-LMR | 1.000 | 1.000 | 0.914 |
Negative urgency | 1.000 | 1.000 | 0.878 |
Lack of perseverance | 1.000 | 1.000 | 0.949 |
Lack of premeditation | 0.990 | 0.999 | 0.986 |
Positive urgency | 1.000 | 1.000 | 0.798 |
Sensation seeking | 1.000 | 1.000 | 0.945 |