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Table 3 Reproductive system abnormalities in adolescent female epilepsy patients before and after VPA initial treatment (n = 40)

From: The safety of valproic acid treatment in children with epilepsy: a retrospective real-world research

Symptom/examination

VPA initial treatment

P value

Before

After

Menstrual disorder or dysmenorrhea

1 (5.0)

5 (20.0)

0.205

Ovarian cystic mass

2 (9.5)

4 (15.4)

0.678

  1. VPA valproic acid