Fig. 1

Case–control differences of regional morphometric similarities. a The mean regional morphometric similarity network (MSN) pattern of healthy controls (HC) and individuals with mesial temporal lobe epilepsy (mTLE). b Case–control comparison (t-map) of MSN between mTLE and HC, eight regions showed significance. c Case–control comparison (t-map) of MSN between mTLE with hippocampal sclerosis (HS) and controls, with ten regions showing significant differences. d Scatterplot of the mean MSN in control (x-axis) and TLE-HC t value (y-axis) (Pearson’s r(150) = 0.35, Pspin = 0.004). e Scatterplot of the mean MSN in control (x-axis) and t value in TLE withHS (y-axis)